Secondary hemostasis refers to:

Secondary hemostasis refers to:

• A. The coagulation cascade
• B. Vascular spasm
• C. Clot lysis
• D. Platelet plug formation

Answer: (A)

Secondary hemostasis is the coagulation cascade that stabilizes a formed plug by producing a fibrin mesh. After an injury, platelets rush in to form a temporary platelet plug (primary hemostasis) and vessels may constrict (vascular spasm). But the lasting clot is reinforced by a series of proteolytic activations that generate thrombin, which converts fibrinogen to fibrin to seal the break. Clot lysis is the later process of dissolving the clot, and platelet plug formation is the initial response, not the reinforcement step.

Secondary hemostasis is the coagulation cascade that stabilizes a formed plug by producing a fibrin mesh. After an injury, platelets rush in to form a temporary platelet plug (primary hemostasis) and vessels may constrict (vascular spasm). But the lasting clot is reinforced by a series of proteolytic activations that generate thrombin, which converts fibrinogen to fibrin to seal the break. Clot lysis is the later process of dissolving the clot, and platelet plug formation is the initial response, not the reinforcement step.