Ketone in urine indicates which condition?

Ketone in urine indicates which condition?

• A. Liver disease
• B. Urinary tract infection
• C. Renal failure
• D. Diabetes mellitus

Answer: (D)

Ketone bodies in urine show that fat is being burned for energy because glucose isn’t being used properly. In diabetes mellitus, especially when insulin is deficient or ineffective, cells can’t take up glucose despite high blood sugar. This makes the body feel starved and it starts breaking down fat, producing ketone bodies in the liver that spill into the urine (ketonuria). This situation is a common sign of poor glycemic control and can lead toward diabetic ketoacidosis if not addressed. The other conditions listed don’t centrally cause ketonuria in the same way, so diabetes mellitus is the most direct association.

Ketone bodies in urine show that fat is being burned for energy because glucose isn’t being used properly. In diabetes mellitus, especially when insulin is deficient or ineffective, cells can’t take up glucose despite high blood sugar. This makes the body feel starved and it starts breaking down fat, producing ketone bodies in the liver that spill into the urine (ketonuria). This situation is a common sign of poor glycemic control and can lead toward diabetic ketoacidosis if not addressed. The other conditions listed don’t centrally cause ketonuria in the same way, so diabetes mellitus is the most direct association.